Remitting seronegative symmetrical synovitis with pitting edema syndrome in individuals with type 2 diabetes mellitus or impaired glucose tolerance

Kohta Oyama; Jun-Ichi Taniguchi; Rieko Goto; Kunihiko Matsui

doi:10.1016/j.diabres.2015.06.007

Remitting seronegative symmetrical synovitis with pitting edema syndrome in individuals with type 2 diabetes mellitus or impaired glucose tolerance

Diabetes Res Clin Pract. 2015 Oct;110(1):e5-e8. doi: 10.1016/j.diabres.2015.06.007. Epub 2015 Jul 29.

Authors

Kohta Oyama¹, Jun-Ichi Taniguchi², Rieko Goto¹, Kunihiko Matsui¹

Affiliations

¹ Center for Community and General Medicine, Kumamoto University Hospital, 1-1-1 Honjyo, Chuo-ku, Kumamoto, 8608556, Japan.
² Center for Community and General Medicine, Kumamoto University Hospital, 1-1-1 Honjyo, Chuo-ku, Kumamoto, 8608556, Japan. Electronic address: tanijun@mac.com.

PMID: 26293448
DOI: 10.1016/j.diabres.2015.06.007

Abstract

An association between remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome and insulin or dipeptidyl peptidase-4 (DPP4) inhibitor therapy were previously reported. We encountered four cases of RS3PE syndrome with type 2 diabetes mellitus or impaired glucose tolerance (IGT) without insulin or DPP4 inhibitor medication.

Keywords: Diabetes mellitus; Impaired glucose tolerance; Remitting seronegative symmetrical synovitis with pitting edema.

Publication types

Case Reports

MeSH terms

Aged
Diabetes Mellitus, Type 2 / complications
Diabetes Mellitus, Type 2 / diagnosis*
Diabetes Mellitus, Type 2 / drug therapy
Edema / complications
Edema / diagnosis*
Female
Glucose Intolerance / complications
Glucose Intolerance / diagnosis*
Humans
Hypoglycemic Agents / therapeutic use
Male
Middle Aged
Syndrome
Synovitis / complications
Synovitis / diagnosis*

Substances

Hypoglycemic Agents