Tropical leg ulcers in children: more than yaws

Trop Doct. 2016 Apr;46(2):90-3. doi: 10.1177/0049475515599326. Epub 2015 Aug 19.

Abstract

The management of yaws has changed in recent years. Mass treatment with oral azithromycin has replaced intramuscular benzathine benzylpenicillin. Treponemal and non-treponemal serology (equivalent to TPHA and RPR) point-of-care blood testing is now available. In addition, recent studies in yaws endemic regions have shown that a significant number of leg ulcers in children which are clinically suggestive of yaws are caused by Haemophilus ducreyi. It is noteworthy that the World Health Organization has also set the ambitious goal to eliminate yaws by 2020.

Keywords: Bacterial infection; disease control; skin and connective tissue; treatment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Azithromycin / administration & dosage
  • Azithromycin / therapeutic use
  • Child
  • Disease Eradication
  • Humans
  • Leg Ulcer / microbiology
  • Penicillin G Benzathine / administration & dosage
  • Penicillin G Benzathine / therapeutic use
  • Point-of-Care Systems
  • Treponema pallidum / isolation & purification
  • Vanuatu / epidemiology
  • Yaws / drug therapy
  • Yaws / epidemiology*
  • Yaws / microbiology
  • Yaws / prevention & control

Substances

  • Anti-Bacterial Agents
  • Azithromycin
  • Penicillin G Benzathine