Chemokine ligand 9 modulates cardiac repolarization via Cxcr3 receptor binding

Int J Cardiol. 2015 Dec 15:201:49-52. doi: 10.1016/j.ijcard.2015.07.096. Epub 2015 Jul 31.

Authors

Brendon P Scicluna¹, Carol Ann Remme¹, Mathilde Rivaud¹, Arthur A M Wilde¹, Connie R Bezzina², Arie O Verkerk³

Affiliations

¹ Department of Clinical and Experimental Cardiology, Academic Medical Center, Amsterdam, The Netherlands.
² Department of Clinical and Experimental Cardiology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: C.R.Bezzina@amc.uva.nl.
³ Department of Anatomy, Embryology and Physiology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: A.O.Verkerk@amc.uva.nl.

PMID: 26288327
DOI: 10.1016/j.ijcard.2015.07.096

No abstract available

Keywords: Action potential; Chemokine; Cxcl9; Cxcr3; L-type Ca(2+) current; Repolarization.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cells, Cultured
Chemokine CXCL9 / metabolism*
Male
Membrane Potentials / physiology
Mice
Myocytes, Cardiac / metabolism*
Protein Binding / physiology
Receptors, CXCR3 / metabolism*

Substances

Chemokine CXCL9
Cxcl9 protein, mouse
Cxcr3 protein, mouse
Receptors, CXCR3