New Polyprenylated Phloroglucinol and Other Compounds Isolated from the Fruits of Clusia nemorosa (Clusiaceae)

Molecules. 2015 Aug 6;20(8):14326-33. doi: 10.3390/molecules200814326.

Abstract

Clusia nemorosa has been widely used in folk medicine to treat various ailments, including headaches and inflammation. Investigation of the fruits of Clusia nemorosa (Clusiaceae) led to the isolation and characterization of a new phloroglucinol derivative, named 6S,8S,28S-nemorosic acid (1), together with seven known compounds: friedelin (2), β-sitosterol (3), stigmasterol (4), β-sitosterol glycoside (5), kaempferol (6), quercetin (7) and dimethyl citrate (8). The structures were determined by extensive 1D- and 2D-NMR, CD and MS spectroscopic analyses.

Keywords: Clusia nemorosa; Clusiaceae; flavonoid; nemorosic acid; phloroglucinol; triterpenoid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Clusiaceae / chemistry*
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification
  • Fruit / chemistry
  • Magnetic Resonance Imaging
  • Medicine, Traditional
  • Nuclear Magnetic Resonance, Biomolecular
  • Phloroglucinol / chemistry*
  • Phloroglucinol / isolation & purification

Substances

  • Flavonoids
  • Phloroglucinol