Hemostatic Disorders in Hormonally Active Pituitary Tumors

Exp Clin Endocrinol Diabetes. 2015 Oct;123(9):548-52. doi: 10.1055/s-0035-1555889. Epub 2015 Aug 18.

Abstract

Endocrinopathies encompass heterogeneous diseases that can lead to hemostasis disorders at various stages over their clinical course. Normal hemostasis requires an equilibrium between the processes of coagulation and fibrinolysis, which depend on multiple activators and inhibitors. To date, the influence of various hormonal disorders on the hemostatic system has been assessed many times. The aim of this review was to analyze hemostasis abnormalities that occur in patients with hormonally active pituitary tumors: corticotropinoma, somatotropinoma, prolactinoma, gonadotropinoma and thyrotropinoma. Authors discuss studies that examined coagulation and hemostasis parameters among patients with these tumors, as well as analyze antithrombotic prophylaxis approach for endogenous hypercortisolemia subjects in particular.

Publication types

  • Review

MeSH terms

  • Hemostatic Disorders / blood*
  • Hemostatic Disorders / drug therapy*
  • Hemostatic Disorders / etiology*
  • Humans
  • Pituitary Neoplasms / blood*