Microphthalmia-associated transcription factor regulates skin melanoblast migration by repressing the melanoma cell adhesion molecule

Exp Dermatol. 2016 Jan;25(1):74-6. doi: 10.1111/exd.12835. Epub 2015 Sep 15.

Authors

Chunbao Rao^{1

2

3}, Zhongyuan Su^{1

2}, Huirong Li^{1

2}, Xiaoyin Ma^{1

2}, Xiaozi Zheng¹, Yin Liu¹, Fan Lu², Jia Qu², Ling Hou^{1

2}

Affiliations

¹ Laboratory of Developmental Cell Biology and Disease, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
² State Key Laboratory Cultivation Base and Key Laboratory of Vision Science of Ministry of Health and Zhejiang Provincial Key Laboratory of Ophthalmology, Wenzhou Medical University, Wenzhou, China.
³ The Eighth People's Hospital of Dongguan, Dongguan Institute of Pediatrics, Dongguan, China.

PMID: 26284703
DOI: 10.1111/exd.12835

No abstract available

Keywords: MCAM; MITF; melanocyte; migration; neural crest.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
CD146 Antigen / genetics
CD146 Antigen / metabolism
Cell Adhesion
Cell Line
Cell Movement
Gene Expression Regulation, Neoplastic*
Green Fluorescent Proteins / metabolism
Hair Follicle / metabolism
Melanocytes / cytology
Melanoma / metabolism*
Mice
Microphthalmia-Associated Transcription Factor / genetics
Microphthalmia-Associated Transcription Factor / metabolism*
Skin / metabolism*
Skin Neoplasms / metabolism*
Wound Healing

Substances

CD146 Antigen
Mcam protein, mouse
Microphthalmia-Associated Transcription Factor
Mitf protein, mouse
Green Fluorescent Proteins