Crystal structure of ethyl 2-(2,4,5-tri-meth-oxy-phen-yl)quinoline-4-carboxyl-ate

T O Shrungesh Kumar; S Naveen; M N Kumara; K M Mahadevan; N K Lokanath

doi:10.1107/S2056989015011706

Crystal structure of ethyl 2-(2,4,5-tri-meth-oxy-phen-yl)quinoline-4-carboxyl-ate

Acta Crystallogr E Crystallogr Commun. 2015 Jun 27;71(Pt 7):o514-5. doi: 10.1107/S2056989015011706. eCollection 2015 Jul 1.

Authors

T O Shrungesh Kumar¹, S Naveen², M N Kumara³, K M Mahadevan¹, N K Lokanath⁴

Affiliations

¹ Department of Chemistry, Kuvempu University, Jnanasahyadri, Shankaraghatta 577 451, India.
² Institution of Excellence, University of Mysore, Manasagangotri, Mysore 570 006, India.
³ Department of Chemistry, Yuvaraja's College, University of Mysore, Mysore 570 005, India.
⁴ Department of Studies in Physics, University of Mysore, Manasagangotri, Mysore 570 006, India.

Abstract

In the title compound, C21H21NO5, the dihedral angle between the quinoline ring system (r.m.s. deviation = 0.028 Å) and the tri-meth-oxy-benzene ring is 43.38 (5)°. The C atoms of the meth-oxy groups deviate from their attached benzene ring by -0.396 (2), -0.049 (2) and 0.192 (2) Å for the ortho-, meta- and para-substituents, respectively. The pendant ethyl chain is disordered over two orientations in a 0.527 (5):0.473 (5) ratio. A short intra-molecular C-H⋯O contact closes an S(6) ring. In the crystal, inversion dimers linked by pairs of weak C-H⋯O inter-actions generate R 2 (2)(6) loops. The dimers are linked by further C-H⋯O inter-actions to generate [1-10] chains.

Keywords: C—H⋯O interactions; crystal structure; hydrogen bonding; quinoline; quinolone-4-ethyl carboxylate.