Direct Exchange of Oxygen and Selenium Atoms in the 1,2,5-Oxadiazoles and 1,2,5-Selenadiazoles by Action of Sulfur Monochloride

Molecules. 2015 Aug 12;20(8):14522-32. doi: 10.3390/molecules200814522.

Abstract

A short synthetic approach to fused 1,2,5-thiadiazoles from the corresponding 1,2,5-oxadiazoles and 1,2,5-selenadiazoles has been developed. Mono- and bis(1,2,5-thiadiazoles) were selectively obtained in high yields. The pathways for these novel reactions were discussed.

Keywords: 1,2,5-oxadiazoles; 1,2,5-selenadiazoles; 1,2,5-thiadiazoles; sulfur monochloride.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Oxadiazoles / chemical synthesis
  • Oxadiazoles / chemistry*
  • Oxygen / chemistry
  • Selenium / chemistry*
  • Sulfur Compounds / chemical synthesis
  • Sulfur Compounds / chemistry*
  • Thiadiazoles / chemical synthesis
  • Thiadiazoles / chemistry*

Substances

  • Oxadiazoles
  • Sulfur Compounds
  • Thiadiazoles
  • Selenium
  • sulfur monochloride
  • Oxygen