Digital technologies for cognitive assessment to accelerate drug development in Alzheimer's disease

Clin Pharmacol Ther. 2015 Nov;98(5):475-6. doi: 10.1002/cpt.212. Epub 2015 Sep 8.

Abstract

For many neurological and psychiatric diseases, novel therapeutics have been elusive for decades. By focusing on attention interference in Alzheimer's disease (AD), we provide a future vision on how emerging mobile, computer, and device-based cognitive tools are converting classically noisy, subjective, data-poor clinical endpoints associated with neuropsychiatric disease assessment into a richer, scalable, and objective set of measurements. Incorporation of such endpoints into clinical drug trials holds promise for more quickly and efficiently developing new medicines.

Publication types

  • Review

MeSH terms

  • Alzheimer Disease / diagnosis*
  • Alzheimer Disease / drug therapy
  • Alzheimer Disease / psychology
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / drug therapy
  • Cognition Disorders / psychology
  • Drug Discovery / methods*
  • Drug Discovery / trends
  • Humans
  • Smartphone / statistics & numerical data*
  • Smartphone / trends
  • Telemedicine / statistics & numerical data*
  • Telemedicine / trends