Research on split-brain individuals started to flourish approximately 70 years ago and has since then significantly contributed to our understanding of hemispheric specialization. This overview aims to capture the essential of its progress. Amongst other things, the disconnection syndrome is exposed through a description of its manifestations on sensory, motor, and cognitive functions. Ground work and recent studies on split-brain individuals are integrated. Copyright © 2010 John Wiley & Sons, Ltd. For further resources related to this article, please visit the WIREs website.
Copyright © 2010 John Wiley & Sons, Ltd.