Extragastrointestinal stromal tumor of lesser omentum: a challenging radiological and histological diagnosis

Clin Imaging. 2015 Nov-Dec;39(6):1123-7. doi: 10.1016/j.clinimag.2015.07.007. Epub 2015 Jul 16.

Abstract

Extragastrointestinal stromal tumors (EGISTs) are a rare subgroup of gastrointestinal stromal tumors (GISTs), arising from outside the walls of gastrointestinal tubular organs. We report a case of an EGIST of the lesser omentum that represented a diagnostic challenge. Due to its atypical radiologic findings, it was preoperatively mistaken for pedunculated hepatic hemangioma. Histopathologically, it showed epithelioid structure and c-kit negative, very uncommon for GIST. Only a few cases of EGISTs have been previously reported. We discuss imaging and histological features, emphasizing potential pitfalls.

Keywords: CT; GIST; MRI; Primitive omental tumor.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Female
  • Gastrointestinal Stromal Tumors / diagnosis*
  • Gastrointestinal Stromal Tumors / diagnostic imaging
  • Gastrointestinal Stromal Tumors / metabolism
  • Gastrointestinal Stromal Tumors / pathology
  • Humans
  • Liver / diagnostic imaging
  • Liver / metabolism
  • Liver / pathology*
  • Omentum / diagnostic imaging
  • Omentum / metabolism
  • Omentum / pathology*
  • Peritoneal Neoplasms / diagnosis*
  • Peritoneal Neoplasms / diagnostic imaging
  • Peritoneal Neoplasms / metabolism
  • Peritoneal Neoplasms / pathology
  • Proto-Oncogene Proteins c-kit / metabolism*
  • Radiography

Substances

  • Proto-Oncogene Proteins c-kit