What are the predictive factors in the risk and severity of chemotherapy-induced gastrointestinal toxicity?

Future Oncol. 2015;11(17):2367-70. doi: 10.2217/FON.15.138. Epub 2015 Aug 13.

Authors

Rachel J Gibson¹, Joanne M Bowen², Janet K Coller³

Affiliations

¹ Discipline of Anatomy & Pathology, School of Medicine, University of Adelaide, Adelaide SA 5005, Australia.
² Discipline of Physiology, School of Medicine, University of Adelaide, Adelaide SA 5005, Australia.
³ Discipline of Pharmacology, School of Medicine, University of Adelaide, Adelaide SA 5005, Australia.

PMID: 26270862
DOI: 10.2217/FON.15.138

No abstract available

Keywords: TLR; chemotherapy; gastrointestinal toxicity; proinflammatory cytokines.

Publication types

Editorial
Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Antineoplastic Combined Chemotherapy Protocols / adverse effects*
Biomarkers
Cytokines / metabolism
Gastrointestinal Diseases / diagnosis
Gastrointestinal Diseases / drug therapy
Gastrointestinal Diseases / etiology*
Gastrointestinal Diseases / metabolism*
Genetic Variation
Humans
Inflammation Mediators / metabolism
Neoplasms / complications*
Neoplasms / drug therapy
Prognosis
Risk
Severity of Illness Index
Signal Transduction / drug effects
Toll-Like Receptor 4 / antagonists & inhibitors
Toll-Like Receptor 4 / genetics
Toll-Like Receptor 4 / metabolism

Substances

Biomarkers
Cytokines
Inflammation Mediators
Toll-Like Receptor 4