Resection of a juvenile nasoangiofibroma by Le Fort I osteotomy: Experience with 40 cases

J Craniomaxillofac Surg. 2015 Oct;43(8):1501-4. doi: 10.1016/j.jcms.2015.06.032. Epub 2015 Jun 27.

Abstract

Purpose: The aim of this study was to determine the rate of success and complications of juvenile nasoangiofibroma resection by Le Fort I osteotomy.

Material and methods: Data were obtained from the medical records of 40 patients with a diagnosis of juvenile nasoangiofibroma confirmed by anatomopathological examination. All tumors were resected by Le Fort I osteotomy between 1983 and 2010. The data obtained were gender, age, symptoms, sites of invasion, preoperative embolization, routes of surgical access, duration of surgery, complications, need for transfusion, relapses, and follow-up time.

Results: All patients were male, ranging in age from 7 to 27 years. The most common symptom was nasal obstruction, and central nervous system (CNS) invasion was present in 27.5% of cases. Craniotomy was associated with Le Fort I osteotomy in only one case. The mean duration of surgery was 216 min. Complications occurred in 15% of cases, with intraoperative bleeding being the most frequent one. Relapses occurred in 5% of cases. The mean follow-up was 48.8 months.

Conclusion: Exclusively surgical treatment by Le Fort I access proved to be a safe and effective method for the treatment of nasoangiofibromas, permitting the removal of tumors even in patients with extension to the CNS, with a low rate of complications and relapses.

Keywords: Juvenile nasopharyngeal angiofibroma; Le Fort I osteotomy; Surgery.

MeSH terms

  • Adolescent
  • Adult
  • Angiofibroma / pathology
  • Angiofibroma / surgery*
  • Blood Loss, Surgical
  • Blood Transfusion
  • Central Nervous System Neoplasms / pathology
  • Child
  • Embolization, Therapeutic / methods
  • Follow-Up Studies
  • Humans
  • Intraoperative Complications
  • Male
  • Maxilla / surgery*
  • Nasal Obstruction / pathology
  • Neoplasm Invasiveness
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Staging
  • Nose Neoplasms / pathology
  • Nose Neoplasms / surgery*
  • Operative Time
  • Osteotomy, Le Fort / methods*
  • Preoperative Care
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult