Functional Brain Imaging Reveals Rapid Blockade of Abdominal Pain Response Upon Anti-TNF Therapy in Crohn's Disease

Gastroenterology. 2015 Oct;149(4):864-6. doi: 10.1053/j.gastro.2015.05.063. Epub 2015 Aug 8.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Video-Audio Media

MeSH terms

  • Abdominal Pain / drug therapy*
  • Abdominal Pain / immunology
  • Abdominal Pain / physiopathology
  • Abdominal Pain / psychology
  • Anti-Inflammatory Agents / therapeutic use*
  • Biological Products / therapeutic use*
  • Brain / drug effects*
  • Brain / physiopathology
  • Crohn Disease / drug therapy*
  • Crohn Disease / immunology
  • Crohn Disease / physiopathology
  • Crohn Disease / psychology
  • Functional Neuroimaging / methods*
  • Gastrointestinal Agents / therapeutic use*
  • Humans
  • Infliximab / therapeutic use*
  • Magnetic Resonance Imaging*
  • Pain Measurement
  • Pain Perception / drug effects
  • Predictive Value of Tests
  • Signal Transduction / drug effects
  • Time Factors
  • Treatment Outcome
  • Tumor Necrosis Factor-alpha / antagonists & inhibitors*
  • Tumor Necrosis Factor-alpha / immunology

Substances

  • Anti-Inflammatory Agents
  • Biological Products
  • Gastrointestinal Agents
  • Tumor Necrosis Factor-alpha
  • Infliximab