An Update on Hidradenitis Suppurativa (Part I): Epidemiology, Clinical Aspects, and Definition of Disease Severity

Actas Dermosifiliogr. 2015 Nov;106(9):703-15. doi: 10.1016/j.ad.2015.06.004. Epub 2015 Aug 6.
[Article in English, Spanish]

Abstract

Hidradenitis suppurativa is a chronic inflammatory disorder that has attracted increasing attention in recent years due to underestimations of prevalence and the considerable impact of the condition on interpersonal relationships, physical appearance, self-esteem, and body image. Although hidradenitis suppurative has a significant psychological impact on patients and can even cause physical limitations when thick scarring results in limb mobility limitation, until very recently little evidence was available relating to its epidemiology, etiology, or pathogenesis. In this review, we highlight the latest advances in our understanding of the epidemiological and clinical aspects of hidradenitis suppurativa. We will also look at the different classification systems for hidradenitis suppurativa and discuss the emergence of skin ultrasound as a promising technique for monitoring the course of this chronic inflammatory disease.

Keywords: Acne inversa; Acné inversa; Clinical; Clínica; Epidemiology; Epidemiología; Hidradenitis suppurativa; Hidradenitis supurativa; Pathogenesis; Patogenia.

Publication types

  • Review

MeSH terms

  • Abscess / etiology
  • Apocrine Glands / pathology
  • Comorbidity
  • Cutaneous Fistula / etiology
  • Cytokines / physiology
  • Disease Susceptibility
  • Female
  • Hidradenitis Suppurativa* / complications
  • Hidradenitis Suppurativa* / diagnostic imaging
  • Hidradenitis Suppurativa* / epidemiology
  • Hidradenitis Suppurativa* / pathology
  • Humans
  • Male
  • Microbiota
  • Obesity / complications
  • Prevalence
  • Risk Factors
  • Severity of Illness Index
  • Smoking / adverse effects
  • Ultrasonography

Substances

  • Cytokines