[A method for choosing preparations that alter hemoglobin binding to oxygen]

Farmakol Toksikol. 1989 Nov-Dec;52(6):83-5.
[Article in Russian]

Abstract

A simple method for investigating drug effect on hemoglobin oxygen affinity by the estimation of HbO2 (%) in blood with and without drugs after gas mixture saturation (4% O2, 5% CO2, 91% N2) is proposed.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Animals
  • Ascorbic Acid / pharmacology*
  • Humans
  • Hydrogen-Ion Concentration
  • Methods
  • Oxygen / blood
  • Oxyhemoglobins / metabolism*
  • Partial Pressure
  • Piracetam / pharmacology*
  • Protein Binding / drug effects
  • Protein Binding / physiology
  • Pyrrolidinones / pharmacology*

Substances

  • Oxyhemoglobins
  • Pyrrolidinones
  • Ascorbic Acid
  • Oxygen
  • Piracetam