Domiciliary administration of intravenous albumin in congenital nephrotic syndrome

Pediatr Nephrol. 2015 Nov;30(11):2045-50. doi: 10.1007/s00467-015-3177-4. Epub 2015 Aug 7.

Abstract

Background: Early management of congenital nephrotic syndrome invariably includes the frequent administration of intravenous human albumin solution. The safety and feasibility of intravenous administration of albumin in the patients' home setting has not previously been reported.

Case-diagnosis/treatment: We report a series of seven paediatric patients whose parents were trained in the administration of albumin via a central venous catheter at home, with the aim of minimising hospital admission or attendances. We describe the clinical course of these patients and complication rates ascribed to this strategy.

Conclusions: Our results demonstrate that home albumin infusion can be performed safely.

Keywords: Central venous catheter; Community care; Nephrotic syndrome.

MeSH terms

  • Albumins / administration & dosage*
  • Central Venous Catheters
  • Female
  • Home Care Services*
  • Humans
  • Infant
  • Infant, Newborn
  • Infusions, Intravenous
  • Male
  • Nephrotic Syndrome / drug therapy*

Substances

  • Albumins

Supplementary concepts

  • Nephrosis, congenital