Recent Molecular Advances in Our Understanding of Glioma

Cureus. 2015 Jul 23;7(7):e287. doi: 10.7759/cureus.287. eCollection 2015 Jul.

Abstract

Our molecular understanding of glioma has undergone a sea change over the last decade. In this review, we discuss two recent articles that employed whole genome sequencing to subclassify gliomas vis-à-vis known molecular alterations. We further discuss the relevance of these findings vis-à-vis current treatment paradigms.

Keywords: 1p/19q; glioblastoma; glioma; idh; neuro-oncology; precision medicine; tert.

Publication types

  • Review