Combating Superbug Without Antibiotic on a Postamputation Wound in a Patient with Diabetic Foot

Int J Low Extrem Wounds. 2016 Mar;15(1):74-7. doi: 10.1177/1534734615595736. Epub 2015 Aug 2.

Abstract

Diabetic foot is a kind of limb- and life-threatening complication that is difficult to treat with conventional therapy, especially when accompanied with peripheral arterial insufficiency and severe infection. We present a diabetic patient with a postamputation wound infected by multidrug-resistant Acinetobacter baumannii/haemolyticus, which was resistant to almost all antibiotics. As the clinical response to antimicrobial therapy was poor, antibiotic was discontinued. Autologous platelet-rich gel with anticoagulation, negative pressure wound therapy, and improvement of microcirculation were used successfully to eradicate infection of the superbug and achieve final wound closure.

Keywords: autologous platelet-rich gel; diabetic foot; multidrug-resistant bacterial infection; negative pressure wound therapy.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged, 80 and over
  • Amputation, Surgical*
  • Anti-Bacterial Agents
  • Combined Modality Therapy
  • Diabetic Foot / surgery*
  • Humans
  • Male
  • Surgical Wound Infection / therapy*

Substances

  • Anti-Bacterial Agents