Evanescent wave fluorescence biosensors: Advances of the last decade

Chris Rowe Taitt; George P Anderson; Frances S Ligler

doi:10.1016/j.bios.2015.07.040

Evanescent wave fluorescence biosensors: Advances of the last decade

Biosens Bioelectron. 2016 Feb 15:76:103-12. doi: 10.1016/j.bios.2015.07.040. Epub 2015 Jul 20.

Authors

Chris Rowe Taitt¹, George P Anderson¹, Frances S Ligler²

Affiliations

¹ Center for Bio/Molecular Science and Engineering, US Naval Research Laboratory, 4555 Overlook Ave SW, Washington, DC 20375-5348, USA.
² UNC-Chapel Hill and NC State University Department of Biomedical Engineering, 911 Oval Drive, Raleigh, NC 27695-7115, USA. Electronic address: Fsligler@ncsu.edu.

Abstract

Biosensor development has been a highly dynamic field of research and has progressed rapidly over the past two decades. The advances have accompanied the breakthroughs in molecular biology, nanomaterial sciences, and most importantly computers and electronics. The subfield of evanescent wave fluorescence biosensors has also matured dramatically during this time. Fundamentally, this review builds on our earlier 2005 review. While a brief mention of seminal early work will be included, this current review will focus on new technological developments as well as technology commercialized in just the last decade. Evanescent wave biosensors have found a wide array applications ranging from clinical diagnostics to biodefense to food testing; advances in those applications and more are described herein.

Keywords: Applications; Evanescent wave; Fluorescence; Optical biosensor.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Biosensing Techniques / methods
Biosensing Techniques / trends*
Clinical Laboratory Techniques / methods*
Fiber Optic Technology / methods*
Fluorescence
Humans

Abstract

Publication types

MeSH terms

Grants and funding