The number of cancer survivors is progressively increasing. Despite the significant progress in the cancer therapies, we are facing the emerging concern of the late side effects and/or psycosocial problems that require diversified follow-up. Healthcare models supporting the oncological patient's needs should be established to improve the quality of life after the diagnosis of oncological disease. Several care models have been proposed - mainly focused on the pediatric population - although further research is needed to optimize the programs. Furthermore, the heterogeneity in existing survivorship care should be addressed: the individual patient characteristics and risk factors (histology, treatment received, age, performance status, comorbidities, lifestyle, behavior risk) should be considered. An efficient cooperation between the General practitioner and the Oncologic team is needed.