Recent Applications of Oxetanes in the Synthesis of Heterocyclic Compounds

Christian A Malapit; Amy R Howell

doi:10.1021/acs.joc.5b01255

Recent Applications of Oxetanes in the Synthesis of Heterocyclic Compounds

J Org Chem. 2015 Sep 4;80(17):8489-95. doi: 10.1021/acs.joc.5b01255. Epub 2015 Aug 19.

Authors

Christian A Malapit¹, Amy R Howell¹

Affiliation

¹ Department of Chemistry, University of Connecticut , Storrs, Connecticut 06269-3060, United States.

PMID: 26225624
DOI: 10.1021/acs.joc.5b01255

Abstract

Oxetanes are valuable intermediates in organic synthesis, and strategic manipulations of this strained heterocycle continue to emerge. In this Synopsis, recent, distinct approaches to construct heterocyclic systems using oxetanes are described. These include ring expansion, ring opening, and C-2 functionalization.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.