MR enterography under the age of 10 years: a single institutional experience

Pediatr Radiol. 2016 Jan;46(1):43-9. doi: 10.1007/s00247-015-3431-8. Epub 2015 Jul 30.

Abstract

Background: MR enterography (MRE) plays a major role in the imaging of pediatric patients with inflammatory bowel disease (IBD) but can be challenging to perform in young children.

Objective: To review our institutional experience regarding the performance of MRE in children younger than 10 years of age, including the use of general anesthesia (GA).

Materials and methods: Institutional review board approval was obtained. Radiology and anesthesia records were searched to identify MRE exams in children younger than 10 years old between June 2009 and May 2013. The following information was documented: demographics, indications for MRE, use of GA, imaging diagnoses, and documented GA-related side effects or adverse events. Imaging was reviewed to document study length, quality and progression of oral contrast material.

Results: One hundred six children (59 boys [56%]) younger than 10 years old underwent 119 MRE examinations (age range: 1 month to 9 years, 11 months). Common indications for MRE included known IBD (42%) and suspected IBD (38%). One hundred ten (92%) examinations were performed under GA. Mean exam length was 52 ± 13 min for GA patients with a range of 31--113 min. Median time under GA was 155 min. Oral contrast material reached the terminal ileum in 31%. Side effects/adverse events associated with GA were uncommon and minor, including transient nausea in 13 children (11%) and emesis in 9 (8%).

Conclusion: Diagnostic-quality MRE can be performed successfully in young children. The majority of MRE exams were performed under GA, with only occasional minor side effects/adverse events.

Keywords: Children; Crohn disease; General anesthesia; Inflammatory bowel disease; Magnetic resonance enterography; Oral contrast.

MeSH terms

  • Administration, Oral
  • Child
  • Child, Preschool
  • Contrast Media / adverse effects
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Inflammatory Bowel Diseases / epidemiology
  • Inflammatory Bowel Diseases / pathology*
  • Magnetic Resonance Imaging / adverse effects
  • Magnetic Resonance Imaging / methods
  • Magnetic Resonance Imaging / statistics & numerical data*
  • Male
  • Meglumine / adverse effects
  • Meglumine / analogs & derivatives*
  • Michigan / epidemiology
  • Nausea / chemically induced*
  • Nausea / diagnosis
  • Nausea / epidemiology
  • Organometallic Compounds / adverse effects*
  • Prevalence
  • Retrospective Studies
  • Risk Factors
  • Vomiting / chemically induced*
  • Vomiting / diagnosis
  • Vomiting / epidemiology

Substances

  • Contrast Media
  • Organometallic Compounds
  • gadobenic acid
  • Meglumine