[Sub-threshold prostate-specific antigen levels after resection of metachronous pulmonary metastases]

Urologe A. 2015 Oct;54(10):1425-8. doi: 10.1007/s00120-015-3923-z.
[Article in German]

Abstract

Radical prostatectomy is a curative therapy for prostate cancer with a lifetime follow-up because there is a high risk of recurrence, especially in the first years of follow-up. In our case disseminated metachronous pulmonary metastases were detected by imaging 4 years after prostatectomy because of elevated levels of serum prostate-specific antigen (PSA). After complete resection of the thoracic metastases the PSA levels have remained below the detection threshold with a recurrence-free survival of 24 months. This case demonstrates that the resection of pulmonary metastases may also be useful for specific individual patients with prostate cancer.

Keywords: Prostatectomy; Pulmonary metastases; Relapse; Resection, metastases; Survival, progression-free.

Publication types

  • Case Reports

MeSH terms

  • Biomarkers, Tumor / blood
  • Humans
  • Kallikreins / blood*
  • Lung Neoplasms / secondary*
  • Lung Neoplasms / surgery*
  • Male
  • Middle Aged
  • Neoplasms, Second Primary / pathology
  • Neoplasms, Second Primary / surgery*
  • Prostate-Specific Antigen / blood*
  • Prostatic Neoplasms / blood*
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / surgery*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Treatment Outcome

Substances

  • Biomarkers, Tumor
  • KLK3 protein, human
  • Kallikreins
  • Prostate-Specific Antigen