Imiquimod and Photodynamic Therapy Are Useful in the Treatment of Porokeratosis in Children with Bone Marrow Transplantation

Pediatr Dermatol. 2015 Nov-Dec;32(6):e291-3. doi: 10.1111/pde.12654. Epub 2015 Jul 29.

Abstract

Porokeratosis is an uncommon disorder that affects keratinization. Immunosuppression may favor the development of porokeratotic lesions. Patients who receive allogenic transplants represent a therapeutic challenge to dermatologists. We report two cases of porokeratosis in children with bone marrow transplant and their excellent response to imiquimod and photodynamic therapy.

Publication types

  • Case Reports

MeSH terms

  • Adjuvants, Immunologic / therapeutic use*
  • Aminoquinolines / therapeutic use*
  • Bone Marrow Transplantation / adverse effects*
  • Child
  • Humans
  • Imiquimod
  • Infant
  • Male
  • Photochemotherapy / methods*
  • Porokeratosis / drug therapy*
  • Porokeratosis / etiology

Substances

  • Adjuvants, Immunologic
  • Aminoquinolines
  • Imiquimod