Abstract
Natural abundance (13)C NMR spectra of biological extracts are recorded in a single scan provided that the samples are hyperpolarized by dissolution dynamic nuclear polarization combined with cross polarization. Heteronuclear 2D correlation spectra of hyperpolarized breast cancer cell extracts can also be obtained in a single scan. Hyperpolarized NMR of extracts opens many perspectives for metabolomics.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Biological Products / chemistry*
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Breast Neoplasms / metabolism
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Breast Neoplasms / pathology
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Carbon Isotopes / chemistry
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Cell Line, Tumor
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Female
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Humans
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Magnetic Resonance Spectroscopy*
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Nuclear Magnetic Resonance, Biomolecular
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Plants / chemistry*
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Plants / metabolism
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Solanum lycopersicum / chemistry
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Solanum lycopersicum / metabolism
Substances
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Biological Products
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Carbon Isotopes