[Clinical Efficacy of Supplementary Treatment of Gukang Capsules to the Elder Patients with Fracture of Distal Radius]

Zhong Yao Cai. 2015 Jan;38(1):193-6.
[Article in Chinese]

Abstract

Objective: To study the clinical efficacy of supplementary treatment of tukang Capsules to the elder patients with fracture of the distal radius.

Methods: A total of 108 elder patients with fracture of the distal radius diagnosed by X-ray,who visited orthopedics department of Pu' ai Hospital in January 2012 - December 2013, were randomly divided into observation group and control group. Cases in both groups received the operation of internal fixation by T-type plate. Cases in control group received oral Calcium Carbonate Tablets, and cases in observation group received Gukang Capsules besides Calcium Carbonate Tablets. Treatment duration was four weeks. The painful and swelling degree of wrist joints, levels of type I propeptide carboxy-terminal procollagen (P I CP) and bone glaprotein(BGP) in serum were compared. Hospitalization and fracture healing time, as well as recovery condition of wrist joints in the sixth month after operation were compared.

Results: The VAS of both groups was not significantly different before operation and in the 28th day after operation(P >0. 05), but the VAS in observation group was significantly lower than that in control group in the 3rd,5th, 7th, 14th and 21th day after operation(P <0. 01). The swelling scale of both groups was not significantly different before operation and in the 28th day after operation(P >0. 05), but the swelling scale in observation group was significantly lower than that in control group in the 3rd, 5th, 7th, 14th and 21th day after operation(P <0. 01). The levels of P I CP and BGP in serum of both groups were not significantly different before operation(P >0. 05), but the levels of P I CP and BGP in serum of observation groups were significantly higher than that in control group one and two months after operation (P <0. 01). Hospitalization and fracture healing time in observation group was significantly shortened compared with control group (P <0. 05). The effective ratio in observation group was 79. 63%, significantly higher than that in control group (P <0. 05).

Conclusion: Gukang Capsules supplementary to internal fixation by T-type plate has favorable efficacy to fracture of the distal radius, which can reduce pain and swelling, increase levels of P I CP and BGP in serum, as well as promote the heal of fracture and recovery of wrist joints function.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Bone Plates
  • Capsules
  • Collagen Type I / blood
  • Drugs, Chinese Herbal / therapeutic use*
  • Fracture Fixation, Internal*
  • Humans
  • Pain
  • Radius / pathology*
  • Radius Fractures / drug therapy*
  • Treatment Outcome

Substances

  • Capsules
  • Collagen Type I
  • Drugs, Chinese Herbal