Spontaneous Coronary Artery Dissection Misdiagnosed as Takotsubo Cardiomyopathy: A Case Series

Can J Cardiol. 2015 Aug;31(8):1073.e5-8. doi: 10.1016/j.cjca.2015.03.018. Epub 2015 Mar 17.

Abstract

Spontaneous coronary artery dissection (SCAD) and Takotsubo cardiomyopathy (TTC) can both cause myocardial infarction with subsequent normalization of wall motion abnormality. Angiograms of patients with TTC at Vancouver General Hospital were reviewed for SCAD. Clinical and investigational characteristics were recorded. Nine women with nonatherosclerotic SCAD were misdiagnosed as having TTC. Their average age was 55 years. Five patients had hypertension and 4 had emotional or physical stress. Fibromuscular dysplasia was present in 4 women. Wall motion abnormalities corresponded to dissected artery location and subsequently resolved. SCAD should be included in the differential diagnosis of patients suspected of having TTC and coronary angiograms scrutinized for subtle SCAD.

MeSH terms

  • Adult
  • Aged
  • Coronary Angiography
  • Coronary Vessel Anomalies / diagnosis
  • Coronary Vessel Anomalies / etiology*
  • Coronary Vessels / pathology*
  • Diagnosis, Differential
  • Diagnostic Errors*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Takotsubo Cardiomyopathy / complications*
  • Takotsubo Cardiomyopathy / diagnosis
  • Vascular Diseases / congenital*
  • Vascular Diseases / diagnosis
  • Vascular Diseases / etiology

Supplementary concepts

  • Coronary Artery Dissection, Spontaneous