Complete genome sequence of Rhodococcus erythropolis BG43 (DSM 46869), a degrader of Pseudomonas aeruginosa quorum sensing signal molecules

Christian Rückert; Franziska S Birmes; Christine Müller; Heiko Niewerth; Anika Winkler; Susanne Fetzner; Jörn Kalinowski

doi:10.1016/j.jbiotec.2015.07.014

Complete genome sequence of Rhodococcus erythropolis BG43 (DSM 46869), a degrader of Pseudomonas aeruginosa quorum sensing signal molecules

J Biotechnol. 2015 Oct 10:211:99-100. doi: 10.1016/j.jbiotec.2015.07.014. Epub 2015 Jul 22.

Authors

Christian Rückert¹, Franziska S Birmes², Christine Müller², Heiko Niewerth², Anika Winkler¹, Susanne Fetzner³, Jörn Kalinowski⁴

Affiliations

¹ Technology Platform Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Sequenz 1, 33615 Bielefeld, Germany.
² Institute of Molecular Microbiology and Biotechnology, University of Münster, Corrensstraße 3, 48149 Münster, Germany.
³ Institute of Molecular Microbiology and Biotechnology, University of Münster, Corrensstraße 3, 48149 Münster, Germany. Electronic address: fetzner@uni-muenster.de.
⁴ Technology Platform Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Sequenz 1, 33615 Bielefeld, Germany. Electronic address: joern.kalinowski@cebitec.uni-bielefeld.de.

PMID: 26210289
DOI: 10.1016/j.jbiotec.2015.07.014

Abstract

Rhodococcus erythropolis BG43 was isolated from soil and characterized as a degrader of the quorum sensing signal molecules 2-heptyl-3-hydroxy-4(1H)-quinolone (the Pseudomonas quinolone signal, PQS) and 2-heptyl-4(1H)-quinolone, produced by Pseudomonas aeruginosa. The complete genome of R. erythropolis BG43 consists of a circular chromosome and three plasmids, one of them circular and two linear ones. In total, 6158 protein-coding regions were identified. With this genome sequence, the genetic basis of its quorum-quenching ability and possible biotechnological applications can be explored further.

Keywords: Pseudomonas aeruginosa; quorum quenching.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
Genome, Bacterial*
High-Throughput Nucleotide Sequencing
Pseudomonas aeruginosa / metabolism*
Quorum Sensing*
Rhodococcus / genetics*
Signal Transduction*