Topical autologous serum promotes enucleation wound healing in retinoblastoma patients

Madeline K Kwok; Jason C S Yam; Christopher B O Yu; Flora H S Lau

doi:10.1016/j.jaapos.2015.02.016

Topical autologous serum promotes enucleation wound healing in retinoblastoma patients

J AAPOS. 2015 Aug;19(4):375-7. doi: 10.1016/j.jaapos.2015.02.016. Epub 2015 Jul 22.

Authors

Madeline K Kwok¹, Jason C S Yam², Christopher B O Yu³, Flora H S Lau²

Affiliations

¹ Department of Ophthalmology, Hong Kong Eye Hospital, Hong Kong SAR, China; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China. Electronic address: dr.madelinekwok@gmail.com.
² Department of Ophthalmology, Hong Kong Eye Hospital, Hong Kong SAR, China; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
³ Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.

PMID: 26210027
DOI: 10.1016/j.jaapos.2015.02.016

Abstract

Two retinoblastoma patients underwent uneventful enucleations while undergoing perioperative chemotherapy. In both cases the postoperative course was complicated by poor conjunctival wound healing. Administration of topical autologous serum was associated with wound healing and conjunctivalization of these wounds.

Publication types

Case Reports

MeSH terms

Administration, Topical
Biological Therapy / methods*
Child, Preschool
Conjunctival Diseases / therapy*
Eye Enucleation*
Humans
Infant
Male
Retinal Neoplasms / surgery*
Retinoblastoma / surgery*
Serum*
Wound Healing*