A new case of zoonotic onchocercosis in northern Kyushu, Japan

Masako Fukuda; Shigehiko Uni; Yasushi Otsuka; Yuki Eshita; Jun Nakatani; Kazuhiko Ihara; Yasuji Yoshikawa; Mizuki Goto; Sakuhei Fujiwara; Rosli Ramli; Mohd Sofian Azirun; Hiroyuki Takaoka

doi:10.1016/j.parint.2015.07.006

A new case of zoonotic onchocercosis in northern Kyushu, Japan

Parasitol Int. 2015 Dec;64(6):519-21. doi: 10.1016/j.parint.2015.07.006. Epub 2015 Jul 21.

Authors

Affiliations

¹ Research Promotion Institute, Oita University, Oita 879-5598, Japan.
² Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia; Department of Parasitology, Graduate School of Medicine, Osaka City University, Osaka 545-8585, Japan. Electronic address: unishigehiko@um.edu.my.
³ Research Center for the Pacific Islands, Kagoshima University, Kagoshima 890-8580, Japan.
⁴ Department of Infectious Disease Control, Faculty of Medicine, Oita University, Oita 879-5593, Japan.
⁵ Agricultural Research Center, National Agriculture and Food Research Organization, Tsukuba, Ibaraki 305-8666, Japan.
⁶ Department of Orthopedics, Beppu Medical Center, Oita 874-0011, Japan.
⁷ Department of Pathology, Beppu Medical Center, Oita 874-0011, Japan.
⁸ Department of Dermatology, Faculty of Medicine, Oita University, Oita 879-5593, Japan.
⁹ Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.

PMID: 26209456
DOI: 10.1016/j.parint.2015.07.006

Abstract

A case of zoonotic onchocercosis has been found in a resident who lived in Iizuka City, Fukuoka Prefecture, Japan for some time. A 24-year-old male developed a painful nodule on the middle finger of his right hand. The nodule was surgically removed from the vagina fibrosa tendinis of the finger at Beppu Medical Center, Beppu City, Oita Prefecture in 2012. The causative agent was identified as a female Onchocerca dewittei japonica based on its histopathological characteristics. The identity of the filarioid has been confirmed by sequencing the cox1 gene. The present study indicates that the zoonotic onchocercosis caused by O. dewittei japonica has been concentrated in northeast Kyushu.

Keywords: Blackfly; Filarioid; Onchocerca; Wild boar; Zoonosis.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Animals
Base Sequence
DNA, Helminth / genetics
Electron Transport Complex IV / genetics
Fingers / parasitology*
Humans
Japan
Male
Onchocerca / isolation & purification*
Onchocerciasis / diagnosis*
Onchocerciasis / parasitology
Sequence Analysis, DNA
Sus scrofa / parasitology
Swine
Swine Diseases / parasitology
Young Adult
Zoonoses / parasitology*

Substances

DNA, Helminth
Electron Transport Complex IV