Ultraviolet light-mediated drug delivery: Principles, applications, and challenges

Aoune Barhoumi; Qian Liu; Daniel S Kohane

doi:10.1016/j.jconrel.2015.07.018

Ultraviolet light-mediated drug delivery: Principles, applications, and challenges

J Control Release. 2015 Dec 10:219:31-42. doi: 10.1016/j.jconrel.2015.07.018. Epub 2015 Jul 21.

Authors

Aoune Barhoumi¹, Qian Liu¹, Daniel S Kohane²

Affiliations

¹ Laboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA; David H. Koch Institutes for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
² Laboratory for Biomaterials and Drug Delivery, Department of Anesthesiology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA; David H. Koch Institutes for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: daniel.kohane@childrens.harvard.edu.

PMID: 26208426
DOI: 10.1016/j.jconrel.2015.07.018

Abstract

UV light has been extensively employed in drug delivery because of its versatility, ease of manipulation, and ability to induce chemical changes on the therapeutic carrier. Here we review the mechanisms by which UV light affects drug delivery systems. We will present the challenges facing UV-induced drug delivery and some of the proposed solutions.

Keywords: Drug delivery; UV-induced drug delivery.

Publication types

Review

MeSH terms

Drug Delivery Systems*
Humans
Ultraviolet Rays*