DNA-melamine hybrid molecules: from self-assembly to nanostructures

Rina Kumari; Shib Shankar Banerjee; Anil K Bhowmick; Prolay Das

doi:10.3762/bjnano.6.148

DNA-melamine hybrid molecules: from self-assembly to nanostructures

Beilstein J Nanotechnol. 2015 Jun 30:6:1432-8. doi: 10.3762/bjnano.6.148. eCollection 2015.

Authors

Rina Kumari¹, Shib Shankar Banerjee², Anil K Bhowmick³, Prolay Das¹

Affiliations

¹ Department of Chemistry, Indian Institute of Technology Patna, Patna 800013, India.
² Department of Materials Science and Engineering, Indian Institute of Technology Patna, Patna 800013, India.
³ Rubber Technology Centre, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.

Abstract

Single-stranded DNA-melamine hybrid molecular building blocks were synthesized using a phosphoramidation cross-coupling reaction with a zero linker approach. The self-assembly of the DNA-organic hybrid molecules was achieved by DNA hybridization. Following self-assembly, two distinct types of nanostructures in the form of linear chains and network arrays were observed. The morphology of the self-assembled nanostructures was found to depend on the number of DNA strands that were attached to a single melamine molecule.

Keywords: DNA–organic hybrid; melamine; nanostructures; phosphoramidation; self-assembly.