Colchicine is not usually considered a treatment option for cutaneous lesions of Henoch-Schönlein purpura (HSP) in children. We report a case of pediatric HSP with severe chronic and relapsing cutaneous manifestations that were resistant to corticosteroids. Colchicine had remarkable therapeutic efficacy, with positive dechallenge and rechallenge, without any adverse effects.
Conclusion: Colchicine should be considered for chronic, severe cutaneous lesions of pediatric HSP.
What is known: Colchicine is not usually considered a treatment option for cutaneous lesions of Henoch-Schönlein purpura (HSP) in children. What is New: We report a case of pediatric HSP with severe cutaneous manifestations that responded well to colchicine. Colchicine should be considered for chronic cutaneous lesions of HSP in children.
Keywords: Chronic severe cutaneous lesions; Colchicine; Henoch-Schönlein purpura; Immunoglobulin A vasculitis; Leukocytoclastic vasculitis.