Green Synthesis of Bifunctional Fluorescent Carbon Dots from Garlic for Cellular Imaging and Free Radical Scavenging

ACS Appl Mater Interfaces. 2015 Aug 12;7(31):17054-60. doi: 10.1021/acsami.5b03228. Epub 2015 Jul 30.

Abstract

Nitrogen and sulfur codoped carbon dots (CDs) were prepared from garlic by a hydrothermal method. The as-prepared CDs possess good water dispersibility, strong blue fluorescence emission with a fluorescent quantum yield of 17.5%, and excellent photo and pH stabilities. It is also demonstrated that the fluorescence of CDs are resistant to the interference of metal ions, biomolecules, and high ionic strength environments. Combining with low cytotoxicity properties, CDs could be used as an excellent fluorescent probe for cellular multicolor imaging. Moreover, the CDs were also demonstrated to exhibit favorable radical scavenging activity.

Keywords: carbon dots; fluorescence; multicolor imaging; radical scavenging activity; reactive oxygen species.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon / chemistry*
  • Cell Line, Tumor
  • Cell Survival / drug effects
  • Fluorescent Dyes / chemistry*
  • Free Radical Scavengers / chemistry*
  • Garlic / chemistry*
  • Garlic / metabolism
  • Green Chemistry Technology
  • Hot Temperature
  • Humans
  • Hydrogen-Ion Concentration
  • Microscopy, Fluorescence
  • Quantum Dots / chemistry*
  • Quantum Dots / toxicity
  • Quantum Dots / ultrastructure
  • Spectrophotometry, Ultraviolet

Substances

  • Fluorescent Dyes
  • Free Radical Scavengers
  • Carbon