Keratoconus progression after intrastromal corneal ring segment implantation in young patients: Five-year follow-up

J Cataract Refract Surg. 2015 Jun;41(6):1145-52. doi: 10.1016/j.jcrs.2014.08.045.

Abstract

Purpose: To analyze whether implantation of intrastromal corneal ring segments (ICRS) influences the progression of keratoconus in young patients.

Setting: Vissum Corporation, Alicante, Spain.

Design: Retrospective case series.

Methods: Eyes with confirmed progressive keratoconus and ICRS (Intacs or Keraring) were evaluated. The visual, refractive, topographic, and aberrometric outcomes were assessed at 2 preoperative examinations to confirm the progressive nature of each case. The postoperative follow-up was 5 years.

Results: The study evaluated 18 eyes in 15 patients with a mean age of 25.75 years ± 3.59 (SD). All the visual, refractive, and topographic measurements worsened between the 2 preoperative examinations, confirming the progressive nature of the cases. Six months postoperatively, there was improvement in the uncorrected and corrected distance visual acuities (P > .05) and all refractive measurements (P < .05) and the mean keratometry (K) was reduced by 4.48 diopters (D) (P < .01). Immediately after the procedure, the visual and refractive variables improved but then worsened. From 6 months postoperatively to 5 years, the mean K value regressed 3.36 D.

Conclusion: Implantation of ICRS significantly improved the visual, refractive, and topographic parameters in the short term; however, the regression at 5 years suggests that implantation of ICRS does not significantly influence progressive keratoconus in young patients with confirmed progression of the disease.

Financial disclosure: No author has a financial or proprietary interest in any material or method mentioned.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aberrometry
  • Adult
  • Corneal Stroma / physiopathology
  • Corneal Stroma / surgery*
  • Corneal Topography
  • Disease Progression
  • Female
  • Follow-Up Studies
  • Humans
  • Keratoconus / physiopathology*
  • Keratoconus / surgery*
  • Male
  • Prostheses and Implants*
  • Prosthesis Implantation*
  • Refraction, Ocular / physiology
  • Retrospective Studies
  • Visual Acuity / physiology
  • Young Adult