Muscle stem cells on the edge

Curr Opin Genet Dev. 2015 Oct:34:24-8. doi: 10.1016/j.gde.2015.06.006. Epub 2015 Jul 17.

Abstract

Release of muscle stem cells from quiescence involves the coordinated effort of transcription, mRNA stability, and translation. We focus this review on post-transcriptional regulation of muscle stem cells and highlight the impact of deregulated mRNA homeostasis on muscle aging and muscle disease pathogenesis.

Publication types

  • Review

MeSH terms

  • Cell Differentiation / genetics
  • Cell Proliferation / genetics
  • Cellular Senescence / genetics
  • Homeostasis
  • Humans
  • Muscle, Skeletal / cytology*
  • Muscle, Skeletal / growth & development
  • RNA Stability / genetics*
  • RNA, Messenger / genetics*
  • RNA, Messenger / metabolism
  • Signal Transduction / genetics
  • Stem Cells / cytology*
  • Stem Cells / metabolism

Substances

  • RNA, Messenger