Abstract
Enterotoxigenic Escherichia coli (ETEC) strains harbor multiple fimbriae and pili to mediate host colonization, including the type IVb pilus, colonization factor antigen III (CFA/III). Not all colonization factors are well characterized or known in toxin positive ETEC isolates, which may have an impact identifying ETEC isolates based on molecular screening of these biomarkers. We describe a novel coli surface antigen (CS) 8 subtype B (CS8B), a family of CFA/III pilus, in a toxin producing ETEC isolate from a Kenyan collection. In highlighting the existence of this putative CS, we provide the sequence and specific primers, which can be used alongside other ETEC primers previously described.
Keywords:
Enterotoxigenic Escherichia coli; Kenya; coli surface antigen 8 subtype B; colonization factors; type IVb pilins.
© FEMS 2015.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antigens, Surface / analysis*
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Antigens, Surface / genetics
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Child, Preschool
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DNA Primers / genetics
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DNA, Bacterial / chemistry
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DNA, Bacterial / genetics
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Enterotoxigenic Escherichia coli / genetics
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Enterotoxigenic Escherichia coli / immunology*
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Enterotoxigenic Escherichia coli / isolation & purification
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Escherichia coli Infections / microbiology*
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Escherichia coli Proteins / analysis*
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Escherichia coli Proteins / genetics
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Fimbriae, Bacterial / genetics
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Fimbriae, Bacterial / immunology*
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Humans
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Infant
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Infant, Newborn
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Kenya
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Molecular Sequence Data
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Sequence Analysis, DNA
Substances
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Antigens, Surface
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DNA Primers
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DNA, Bacterial
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Escherichia coli Proteins
Associated data
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GENBANK/CEJ09697
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GENBANK/CEJ09698
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GENBANK/CEJ09699
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GENBANK/CEJ09700
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GENBANK/CEJ09701
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GENBANK/CEJ09702
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GENBANK/CEJ09703
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GENBANK/CEJ09704
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GENBANK/CEJ09705
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GENBANK/CEJ09706
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GENBANK/CEJ09707
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GENBANK/CEJ09708
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GENBANK/CEJ09709
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GENBANK/CEJ09710