Recent advances in electrochemical biosensors based on graphene two-dimensional nanomaterials

Yang Song; Yanan Luo; Chengzhou Zhu; He Li; Dan Du; Yuehe Lin

doi:10.1016/j.bios.2015.07.002

Recent advances in electrochemical biosensors based on graphene two-dimensional nanomaterials

Biosens Bioelectron. 2016 Feb 15:76:195-212. doi: 10.1016/j.bios.2015.07.002. Epub 2015 Jul 5.

Authors

Yang Song¹, Yanan Luo¹, Chengzhou Zhu², He Li², Dan Du³, Yuehe Lin⁴

Affiliations

¹ Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, PR China; Department of Mechanical and Material Engineering, Washington State University, Pullman, WA 99164, United States.
² Department of Mechanical and Material Engineering, Washington State University, Pullman, WA 99164, United States.
³ Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, PR China; Department of Mechanical and Material Engineering, Washington State University, Pullman, WA 99164, United States; Paul G. Allen School for Global Animal Health, Washington State University, Pullman, WA 99164, United States. Electronic address: dan.du@mail.ccnu.edu.cn.
⁴ Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, PR China; Department of Mechanical and Material Engineering, Washington State University, Pullman, WA 99164, United States; Paul G. Allen School for Global Animal Health, Washington State University, Pullman, WA 99164, United States. Electronic address: yuehe.lin@wsu.edu.

PMID: 26187396
DOI: 10.1016/j.bios.2015.07.002

Abstract

Graphene as a star among two-dimensional nanomaterials has attracted tremendous research interest in the field of electrochemistry due to their intrinsic properties, including the electronic, optical, and mechanical properties associated with their planar structure. The marriage of graphene and electrochemical biosensors has created many ingenious biosensing strategies for applications in the areas of clinical diagnosis and food safety. This review provides a comprehensive overview of the recent advances in the development of graphene based electrochemical biosensors. Special attention is paid to graphene-based enzyme biosensors, immunosensors, and DNA biosensors. Future perspectives on high-performance graphene-based electrochemical biosensors are also discussed.

Keywords: DNA sensors; Electrochemical biosensor; Enzyme-based biosensors; Graphene; Immunosensors; Two-dimensional nanomaterials.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Biosensing Techniques / methods*
DNA / chemistry
Electrochemistry / methods*
Enzymes / chemistry
Graphite / chemistry*
Humans
Nanostructures / chemistry*

Substances

Enzymes
Graphite
DNA

Abstract

Publication types

MeSH terms

Substances

Grants and funding