De Novo Whole-Genome Sequence and Annotation of a Leishmania Strain Isolated from a Case of Post-Kala-Azar Dermal Leishmaniasis

Anil Kumar Gupta; Saumya Srivastava; Amit Singh; Sarman Singh

doi:10.1128/genomeA.00809-15

De Novo Whole-Genome Sequence and Annotation of a Leishmania Strain Isolated from a Case of Post-Kala-Azar Dermal Leishmaniasis

Genome Announc. 2015 Jul 16;3(4):e00809-15. doi: 10.1128/genomeA.00809-15.

Authors

Anil Kumar Gupta¹, Saumya Srivastava¹, Amit Singh¹, Sarman Singh²

Affiliations

¹ Division of Clinical Microbiology & Molecular Medicine, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India.
² Division of Clinical Microbiology & Molecular Medicine, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India sarman_singh@yahoo.com.

Abstract

The pathogenesis of post-kala-azar dermal leishmaniasis (PKDL) is complex. Only 5 to 10% of kala-azar patients develop this dermal complication, and it is not known whether this is due to changes in the parasite genome or some host factors. Here, we report the whole-genome sequence and annotated genes of the whole genome of the PKDL strain.