Successful Use of Extracorporeal Membrane Oxygenation in a Neonate With Arterial pH Less Than 6.6

World J Pediatr Congenit Heart Surg. 2015 Jul;6(3):466-9. doi: 10.1177/2150135114558849.

Abstract

Challenges in extracorporeal membrane oxygenation (ECMO) support include defining appropriate patient selection criteria and prognostic factors. Severe acidosis prior to ECMO deployment is often considered a relative contraindication and an independent predictor of mortality. We present a case of a term infant, with persistent pulmonary hypertension of the newborn with severe pre-ECMO acidosis (arterial blood pH 6.596) in whom venoarterial ECMO was instituted successfully without major circuit or patient-associated complications. At seven months of age, he exhibited age-appropriate neurodevelopmental milestones. We therefore report this instance of successful use of ECMO in the setting of extreme acidosis.

Keywords: acidosis; extracorporeal membrane oxygenation; neonate; persistent pulmonary hypertension.

Publication types

  • Case Reports

MeSH terms

  • Acidosis / blood*
  • Acidosis / etiology
  • Acidosis / therapy
  • Extracorporeal Membrane Oxygenation / methods*
  • Humans
  • Hydrogen-Ion Concentration
  • Infant, Newborn
  • Male
  • Persistent Fetal Circulation Syndrome / blood
  • Persistent Fetal Circulation Syndrome / complications
  • Persistent Fetal Circulation Syndrome / therapy*