Formation of multiple pulmonary nodules during treatment with leflunomide

J Bras Pneumol. 2015 May-Jun;41(3):281-4. doi: 10.1590/S1806-37132015000004247.
[Article in English, Portuguese]

Abstract

Pulmonary involvement is one of the extra-articular manifestations of rheumatoid arthritis and can be due to the disease itself or secondary to the medications used in order to treat it. We report the case of a 60-year-old woman who had been diagnosed with rheumatoid arthritis and developed multiple pulmonary nodules during treatment with leflunomide.

O comprometimento pulmonar é uma das manifestações extra-articulares da artrite reumatóide e pode ser devido à própria doença ou secundário às medicações utilizadas para seu tratamento. Este trabalho relata um caso de uma paciente de 60 anos de idade com diagnóstico de artrite reumatoide que evoluiu com múltiplos nódulos pulmonares durante o tratamento com leflunomida.

Publication types

  • Case Reports

MeSH terms

  • Antirheumatic Agents / adverse effects*
  • Arthritis, Rheumatoid / drug therapy*
  • Female
  • Humans
  • Isoxazoles / adverse effects*
  • Leflunomide
  • Middle Aged
  • Multiple Pulmonary Nodules / chemically induced*
  • Multiple Pulmonary Nodules / pathology
  • Rheumatoid Nodule / chemically induced*
  • Rheumatoid Nodule / pathology
  • Tomography, X-Ray Computed

Substances

  • Antirheumatic Agents
  • Isoxazoles
  • Leflunomide