Malignant Triton Tumor of the Kidney. New Location Not Previously Reported

Urol Int. 2017;99(1):121-123. doi: 10.1159/000434639. Epub 2015 Jul 7.

Abstract

Malignant triton tumor (MTT) is a variant of the peripheral nerve sheath tumor. It is very uncommon but shows an aggressive course and limited survival. Half of the cases present symptoms related to neurofibromatosis type 1 disease. There is no standardized treatment, but multimodal approach is the best option. We present the case of a primary MTT located in the kidney, in a 43-year-old woman who received neoadjuvant chemotherapy as first-line treatment followed by surgical resection and adjuvant chemotherapy.

Keywords: Kidney tumor; Malignant triton tumor; Peripheral nerve sheath tumor; Rhabdomyoblastic differentiation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biomarkers, Tumor / genetics
  • Chemotherapy, Adjuvant
  • Fatal Outcome
  • Female
  • Humans
  • Kidney Neoplasms / diagnostic imaging
  • Kidney Neoplasms / genetics
  • Kidney Neoplasms / pathology*
  • Kidney Neoplasms / therapy
  • Neoadjuvant Therapy
  • Nephrectomy
  • Peripheral Nervous System Neoplasms / diagnostic imaging
  • Peripheral Nervous System Neoplasms / genetics
  • Peripheral Nervous System Neoplasms / pathology*
  • Peripheral Nervous System Neoplasms / therapy
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Biomarkers, Tumor