[Histopathological evaluation of the subtotal laryngectomy specimen]

Cir Cir. 2015 Nov-Dec;83(6):537-42. doi: 10.1016/j.circir.2015.05.038. Epub 2015 Jul 7.
[Article in Spanish]

Abstract

Introduction: The goal of conservative surgical treatment of laryngeal cancer is to obtain oncological control with preservation of laryngeal function. The concept of laryngeal function preservation should be understood as the preservation of the patient's ability to breathe normally with neither tracheostomy nor aspiration, and maintaining intelligible speech. This can be achieved by a balance between two fundamental aspects, proper patient selection (based on tumour extension and preoperative laryngeal function), and an adequate histopathological analysis of the surgical specimen. Supracricoid subtotal laryngectomy is the voice conservative surgical technique that offers the best possibility of control in patients with locally advanced laryngeal cancer. The proper histopathological analysis allows staging and selecting patients for adjuvant therapy, avoiding unnecessary ones as well as designing monitoring and surveillance programs based on risk factors.

Objective: To highlight key points in the histopathological evaluation of the surgical specimen of a subtotal laryngectomy.

Conclusion: The proper communication between the surgeon and pathologist, offering complete information on preoperative clinical evaluation and the knowledge of the key points in the evaluation of the surgical specimen (sites of tumour leakage and surgical resection margins) are fundamental parameters to achieve a proper histopathological evaluation of the surgical specimen.

Keywords: Cáncer de laringe; Laringectomía; Laringectomía parcial; Laryngeal cancer; Laryngectomy; Partial laryngectomy.

Publication types

  • English Abstract

MeSH terms

  • Humans
  • Interdisciplinary Communication
  • Laryngeal Neoplasms / pathology*
  • Laryngeal Neoplasms / surgery
  • Laryngectomy / methods*
  • Larynx / pathology*
  • Medical Oncology
  • Neoplasm Grading
  • Neoplasm Invasiveness
  • Organ Sparing Treatments
  • Otolaryngology
  • Pathology, Clinical / methods*
  • Patient Care Team
  • Patient Selection
  • Specimen Handling
  • Vocal Cords