Surgical site infection after primary hip and knee arthroplasty: a cohort study using a hospital database

Infect Control Hosp Epidemiol. 2015 Oct;36(10):1198-207. doi: 10.1017/ice.2015.148. Epub 2015 Jul 8.

Abstract

Background: Hip or knee arthroplasty infection (HKAI) leads to heavy medical consequences even if rare.

Objective: To assess the routine use of a hospital discharge detection algorithm of prosthetic joint infection as a novel additional tool for surveillance.

Methods: A historic 5-year cohort study was built using a hospital database of people undergoing a first hip or knee arthroplasty in 1 French region (2.5 million inhabitants, 39 private and public hospitals): 32,678 patients with arthroplasty code plus corresponding prosthetic material code were tagged. HKAI occurrence was then tracked in the follow-up on the basis of a previously validated algorithm using International Statistical Classification of Disease, Tenth Revision, codes as well as the surgical procedures coded. HKAI density incidence was estimated during the follow-up (up to 4 years after surgery); risk factors were analyzed using Cox regression.

Results: A total of 604 HKAI patients were identified: 1-year HKAI incidence was1.31%, and density incidence was 2.2/100 person-years in hip and 2.5/100 person-years in knee. HKAI occurred within the first 30 days after surgery for 30% but more than 1 year after replacement for 29%. Patients aged 75 years or older, male, or having liver diseases, alcohol abuse, or ulcer sore had higher risk of infection. The inpatient case fatality in HKAI patients was 11.4%.

Conclusions: The hospital database method used to measure occurrence and risk factors of prosthetic joint infection helped to survey HKAI and could optimize healthcare delivery.

Publication types

  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Algorithms
  • Arthroplasty, Replacement, Hip*
  • Arthroplasty, Replacement, Knee*
  • Databases, Factual
  • Female
  • Follow-Up Studies
  • France / epidemiology
  • Hip Prosthesis / adverse effects*
  • Humans
  • Incidence
  • Knee Prosthesis / adverse effects*
  • Male
  • Middle Aged
  • Patient Discharge
  • Population Surveillance
  • Prosthesis-Related Infections / diagnosis
  • Prosthesis-Related Infections / epidemiology*
  • Prosthesis-Related Infections / etiology
  • Retrospective Studies
  • Risk Factors
  • Surgical Wound Infection / diagnosis
  • Surgical Wound Infection / epidemiology*
  • Surgical Wound Infection / etiology
  • Young Adult