Objective: The aim of this study was to investigate whether performing different fertilization technologies (intracytoplasmic sperm injection [ICSI] and in vitro fertilization [IVF]) may affect the result of fertilization in the normal fertilization cycles.
Study design: The authors performed a retrospective analysis of 164 cycles using sibling oocytes in combined IVF/ICSI with achieved a normal fertilization ( ≥ 25%) both conventional IVF and ICSI in this infertility centre.
Results: It was found that there were no differences in 2PN rate (70.25% vs 70.60%), but higher cleavage rate in ICSI than IVF insemination (98.99% vs 96.81%), higher arrested embryos rate in IVF than ICSI in 2PN group (20.00% vs 13.95%), and higher abnormal fertilization IPN (3.87% vs 1.92%) and 3PN (3.63 vs 0.854%) in IVF than ICSI.
Conclusion: There were some differences fertilization outcomes between ICSI and IVF, which may be related to different procedures between two techniques.