Different flavors of Toll guide olfaction

Claudine Neyen; Bruno Lemaitre

doi:10.1016/j.it.2015.06.008

Different flavors of Toll guide olfaction

Trends Immunol. 2015 Aug;36(8):439-41. doi: 10.1016/j.it.2015.06.008. Epub 2015 Jul 3.

Authors

Claudine Neyen¹, Bruno Lemaitre²

Affiliations

¹ Centre for Integrative Genomics, University of Lausanne, Unil-Sorge, Lausanne, CH-1015 Switzerland. Electronic address: claudine.neyen@exeter.oxon.org.
² Global Health Institute, School of Life Sciences, EPFL, Station 19, Lausanne, CH-1015 Switzerland. Electronic address: bruno.lemaitre@epfl.ch.

PMID: 26150191
DOI: 10.1016/j.it.2015.06.008

Abstract

Toll-like receptors are historically linked to immunity across animal phyla, but accumulating evidence suggests they play additional roles in neuronal networks and in cell-cell interactions. Ward and colleagues now identify Toll-6 and Toll-7 as instructive guidance cues during Drosophila olfactory development.

Keywords: Toll; development; olfactory neurons.

MeSH terms

Animals
Drosophila / physiology*
Smell / physiology*
Toll-Like Receptor 6 / physiology*
Toll-Like Receptor 7 / physiology*

Substances

Toll-Like Receptor 6
Toll-Like Receptor 7