Currently, new technologies of timely diagnosis and correction of disorders of carbohydrate metabolism are constantly introducing in intensive care units. The technologies aimed to improve the safety of the patient during intensive care. These methods include continuous monitoring (subcutaneous, intravascular) and the control of blood glucose levels, based on technologies such as enzymatic and electrochemical, fluorescence, infrared and others. Computer technologies proposed an algorithm of glycemic control with mathematical models occupy an important place. One of such algorithms is eMPC, which predicts blood glucose levels and offers physician a choice of a rate of intravenous administration of insulin and the time of further control of the glucose level. Researchers have demonstrated promising results of such technologies in patients in the ICU. Systems of continuous glucose monitoring can improve the safety of patients suffering from diabetes, as well as during intravenous insulin therapy and artifcial feeding.