Oral lichen planus: an update on its pathogenesis

Int J Dermatol. 2015 Sep;54(9):1005-10. doi: 10.1111/ijd.12918. Epub 2015 Jul 3.

Abstract

Oral lichen planus (OLP) is a common T cell-mediated mucocutaneous disease of unknown etiology. A great number of factors have been suggested as relevant to the etiology of this disease. In this article, the authors assemble recent knowledge about the pathogenesis of OLP, discuss some proposed hypotheses, and compare OLP with oral lichenoid lesions.

Publication types

  • Review

MeSH terms

  • Biopsy, Needle
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunity, Cellular / physiology*
  • Immunohistochemistry
  • Immunosuppressive Agents / therapeutic use
  • Lichen Planus, Oral / drug therapy
  • Lichen Planus, Oral / immunology*
  • Lichen Planus, Oral / pathology*
  • Lichenoid Eruptions / drug therapy
  • Lichenoid Eruptions / immunology
  • Lichenoid Eruptions / pathology
  • Male
  • Prognosis
  • Risk Assessment
  • Severity of Illness Index

Substances

  • Immunosuppressive Agents