The role of interleukin-32 against tuberculosis

Cytokine. 2015 Dec;76(2):585-587. doi: 10.1016/j.cyto.2015.06.013. Epub 2015 Jul 3.

Abstract

IL-32 is increasingly recognized to be an important host-protective molecule against tuberculosis. In this commentary, we highlight some of the potential mechanisms by which the immunomodulatory effect of IL-32 occurs against mycobacterial infections but also areas where mechanistic clarifications are needed.

Keywords: Cytokine; Interleukin-32; Tuberculosis.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Humans
  • Interleukins / physiology*
  • Tuberculosis / immunology
  • Tuberculosis / physiopathology*

Substances

  • IL32 protein, human
  • Interleukins